SEDAN Score (post-tPA symptomatic ICH)

SEDAN score (Strbian 2012): predicts symptomatic intracranial hemorrhage after IV thrombolysis (0-6).

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Baseline blood glucose band
> 12.0 mmol/L (> 216 mg/dL) (+2)
Early infarct signs on CT
Yes
Hyperdense cerebral artery sign
Yes
Age
80
Baseline NIHSS
12

Result: SEDAN 6/6: symptomatic ICH risk after thrombolysis ~33.3%.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Risk
symptomatic ICH 1.4% at 0, 2.9% at 1, 8.5% at 2, 12.2% at 3, 21.7% at 4, and 33.3% at the >= 5 stratum.

What you enter

  • Baseline blood glucose band
  • Early infarct signs on CT
  • Hyperdense cerebral artery sign
  • Age (years)
  • Baseline NIHSS
How this is calculated
Components
blood glucose (<= 8.0 / 8.1-12.0 / > 12.0 mmol/L = 0/+1/+2), early infarct signs (+1), dense cerebral artery sign (+1), age > 75 (+1), and NIHSS >= 10 (+1), summed 0-6.

Strbian D, Engelter S, Michel P, et al. Symptomatic intracranial hemorrhage after stroke thrombolysis: the SEDAN score. Ann Neurol. 2012;71(5):634-641. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.