SPISE (Insulin Sensitivity Estimator)
SPISE (Insulin Sensitivity Estimator) - a deterministic tool in Sophie Well's Clinical Scoring & Risk group.
Open the SPISE (Insulin Sensitivity Estimator) → Runs in your browser. No signup, no tracking.
What this is
SPISE (Insulin Sensitivity Estimator) is one of 230 deterministic tools in Sophie Well's Clinical Scoring & Risk group. SPISE (Insulin Sensitivity Estimator) - a deterministic tool in Sophie Well's Clinical Scoring & Risk group.
When to use it
Use this tool when you need a quick, citable reference. Every calculation runs entirely in your browser - no inputs leave your device, no account is required, no AI is involved. The site enforces a strict Content Security Policy and ships no analytics or third-party CDN.
References
Paulmichl K, Hatunic M, Hojlund K, et al. Modification and validation of the triglyceride-to-HDL cholesterol ratio as a surrogate of insulin sensitivity (SPISE). Clin Chem. 2016;62(9):1211-1219. Read the source ↗
Worked example: SPISE 4.6 — suggests insulin resistance (< 5.4 in adolescents).
Sophie Well is a reference and educational tool. Not medical, legal, or financial advice. Does not replace clinician judgment, professional billing review, or legal counsel.