SPINA-GT (Thyroid Secretory Capacity)
SPINA-GT thyroid secretory capacity (Dietrich 2012): a structure-parameter estimate of maximum thyroid hormone output from TSH and free T4; the reference band is ~1.4–8.7 pmol/s.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- TSH
- 1 mU/L
- Free T4
- 16.5 pmol/L
Result: SPINA-GT 4.7 pmol/s — within the ~1.4–8.7 pmol/s reference band.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Reference
- ~1.4–8.7 pmol/s; a low GT indicates reduced thyroid secretory capacity.
What you enter
- TSH
- Free T4
How this is calculated
- Inputs
- TSH (mIU/L) and free T4 (pmol/L) through the published structure-parameter equation (protein-binding factor 6901).
Dietrich JW, Landgrafe-Mende G, Wiora E, et al. Calculated parameters of thyroid homeostasis: emerging tools for differential diagnosis and clinical research. Front Endocrinol (Lausanne). 2016;7:57. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.