Spigelman Stage (Duodenal Polyposis in FAP)
The Spigelman classification of duodenal polyposis in familial adenomatous polyposis.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Number of duodenal polyps
- 3
- Size of the largest polyp
- 3
- Histology
- 3
- Dysplasia
- 3
Result: Spigelman 12 of 12, stage IV.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0 points
- Stage 0. No duodenal adenomas were found, which is established before the score is computed rather than by computing it.
- 1 to 4
- Stage I, mild disease. Only the top of this band is reachable once any adenoma is present.
- 5 to 6
- Stage II, moderate disease.
- 7 to 8
- Stage III, severe disease.
- 9 to 12
- Stage IV, severe disease.
What you enter
- Number of duodenal polyps
- Size of the largest polyp
- Histology
- Dysplasia
Full field descriptions
- Number of duodenal polyps [1 point - 1 to 4 polyps; 2 points - 5 to 20 polyps; 3 points - more than 20 polyps]
- Size of the largest polyp [1 point - 1 to 4 mm; 2 points - 5 to 10 mm; 3 points - more than 10 mm]
- Histology [1 point - tubular; 2 points - tubulovillous; 3 points - villous]
- Dysplasia [1 point - mild (reported as low grade in a two-tiered report); 2 points - moderate (a three-tier grade; a two-tiered report will not contain it); 3 points - severe (reported as high grade in a two-tiered report)]
How this is calculated
- Scoring
- Polyp number, largest polyp size, histology, and dysplasia grade, each worth 1 to 3 points. No parameter has a zero row.
Spigelman AD, Williams CB, Talbot IC, Domizio P, Phillips RK. Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet. 1989;2(8666):783-785. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.