SPAN-100 Index (Age + NIHSS Stroke Prognosis)
SPAN-100 index (Saposnik 2013): age plus NIHSS; an index ≥ 100 (SPAN-100 positive) marks a substantially worse acute-ischemic-stroke prognosis with a much lower favorable-outcome rate.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 80 years
- NIHSS
- 22
Result: SPAN-100 index 102 — SPAN-100 positive (≥ 100): substantially worse prognosis (much lower favorable-outcome rate).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Index
- SPAN-100 = age (years) + NIHSS, dichotomized at 100. SPAN-100 positive when ≥ 100.
- Meaning
- Positive patients have higher mortality/disability and much lower rates of favorable 3-month outcome (≈ 5.6% vs ≈ 55.4% in the NINDS-tPA derivation). A counseling index, not a treatment rule.
What you enter
- Age
- NIHSS (0–42)
How this is calculated
Saposnik G, Guzik AK, Reeves M, Ovbiagele B, Johnston SC. Stroke Prognostication using Age and NIH Stroke Scale: SPAN-100. Neurology. 2013;80(1):21-28. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.