Sano Score (IVIG Resistance, Kawasaki)
Sano score (Sano 2007): predicts IVIG resistance in Kawasaki disease from three pre-treatment labs.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- AST
- 250 IU/L
- Total bilirubin
- 0.5 mg/dL
- CRP
- 9 mg/dL
Result: Sano 2 of 3 — high risk of IVIG resistance (>= 2).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- < 2
- Lower risk of IVIG resistance.
- >= 2
- High risk of IVIG resistance (derivation ~77% sensitivity / ~86% specificity; lower in Western and infant cohorts). A resistance-risk band, not an IVIG or steroid order.
What you enter
- AST (IU/L)
- Total bilirubin (mg/dL)
- CRP (mg/dL)
How this is calculated
- Criteria
- AST >=200 IU/L, total bilirubin >=0.9 mg/dL, CRP >=7 mg/dL; each counts 1 point (0-3).
Sano T, Kurotobi S, Matsuzaki K, et al. Prediction of non-responsiveness to standard high-dose gamma-globulin therapy in patients with acute Kawasaki disease before starting initial treatment. Eur J Pediatr. 2007;166(2):131-137. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.