Renal Failure Index (RFI)

Renal failure index = urine sodium x plasma creatinine / urine creatinine; < 1 favors prerenal azotemia, > 1 favors acute tubular necrosis.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Urine sodium
10 mEq/L
Plasma creatinine
4 mg/dL
Urine creatinine
60 mg/dL

Result: Renal failure index 0.67 — favors prerenal azotemia (< 1).

The tool opens with these values already filled in. Replace them with your own.

What the result means

< 1
Favors prerenal azotemia.
> 1
Favors acute tubular necrosis (UNa x PCr / UCr). Unreliable with diuretics or CKD. A renal index, not a diagnosis.

What you enter

  • Urine sodium
  • Plasma creatinine
  • Urine creatinine
How this is calculated

Espinel CH. The FENa test. Use in the differential diagnosis of acute renal failure. JAMA. 1976;236(6):579-581. (Renal failure index; Miller TR, et al. Ann Intern Med. 1978.) Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.