POP Scale (Organophosphate Poisoning Severity)

The Peradeniya Organophosphorus Poisoning (POP) scale (Senanayake and colleagues 1993), which grades the severity of acute organophosphate poisoning.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Pupil size
Pinpoint
Respiratory rate
20 or more per minute
Heart rate
50 per minute
Whether fasciculation is GENERALIZED
Yes
Whether fasciculation is CONTINUOUS
No
Level of consciousness
Impaired response to verbal command
Seizures
Absent

Result: POP scale 6 of 11

The tool opens with these values already filled in. Replace them with your own.

What the result means

Maximum
11, NOT 12: five parameters score 0-2 but seizures scores 0-1 only.
Pupil
2mm or more = 0; under 2mm = 1; pinpoint = 2. PINPOINT TAKES PRECEDENCE (the levels overlap).
Respiratory
Under 20 = 0; 20 or more = 1; 20 or more WITH central cyanosis = 2.
Heart rate
Above 60 = 0; 41-60 = 1; below 40 = 2. The interval 40 to under 41 is UNSCOREABLE.
Fasciculation
Generalized OR continuous = 1; BOTH = 2. A conjunction, not a severity ladder.
Consciousness
Rational = 0; impaired response = 1; no response = 2.
0 to 3
Mild poisoning.
4 to 7
Moderate poisoning.
8 to 11
Severe poisoning.
Timing
Apply BEFORE treatment: atropine reverses miosis and bradycardia, two of the six parameters.
Scope
NOT a dosing instrument. Atropine is titrated to secretions and oxygenation, not to a score.

What you enter

  • Pupil size.
  • Respiratory rate
  • Heart rate.
  • Whether fasciculation is GENERALIZED.
  • Whether fasciculation is CONTINUOUS.
  • Level of consciousness
  • Seizures.
Full field descriptions
  • Pupil size. PINPOINT TAKES PRECEDENCE over "under 2 mm", which the published levels overlap [at-least-2mm = 2 mm or more, 0 points; under-2mm = Under 2 mm, but not pinpoint, 1 points; pinpoint = Pinpoint, 2 points]
  • Respiratory rate [under-20 = Under 20 per minute, 0 points; at-least-20 = 20 or more per minute, 1 points; at-least-20-cyanosis = 20 or more per minute with central cyanosis, 2 points]
  • Heart rate. Above 60 = 0; 41 to 60 = 1; below 40 = 2. EXACTLY 40 falls in NO published level and is REFUSED.
  • Whether fasciculation is GENERALIZED. Combined with the continuous attribute as a conjunction: either alone scores 1, both score 2.
  • Whether fasciculation is CONTINUOUS. Combined with the generalized attribute as a conjunction: either alone scores 1, both score 2.
  • Level of consciousness [conscious = Conscious and rational, 0 points; impaired = Impaired response to verbal command, 1 points; none = No response to verbal command, 2 points]
  • Seizures. HALF WEIGHT: 0 or 1 only, which is why the maximum is 11 and not 12 [absent = 0 points; present = 1 points]
How this is calculated

Senanayake N, de Silva HJ, Karalliedde L. A scale to assess severity in organophosphorus intoxication: POP scale. Hum Exp Toxicol. 1993;12(4):297-299. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.