Oral Disposition Index (DIo)

Oral disposition index DIo (Utzschneider 2009): the insulinogenic index (ΔI30/ΔG30) times fasting insulin sensitivity (1/I0); a lower value predicts higher future-diabetes risk.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Fasting insulin
8 mU/L
30-min insulin
60 mU/L
Fasting glucose
90 mg/dL
30-min glucose
150 mg/dL

Result: Oral disposition index 0.108 — sensitivity-adjusted β-cell secretion; a lower value predicts higher future-diabetes risk.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Meaning
Sensitivity-adjusted β-cell secretion; a lower DIo predicts higher future-diabetes risk.

What you enter

  • Fasting insulin (I0)
  • 30-min insulin (I30)
  • Fasting glucose (G0)
  • 30-min glucose (G30)
How this is calculated
Formula
Insulinogenic index = ΔInsulin(0–30) / ΔGlucose(0–30); DIo = insulinogenic index × (1 / fasting insulin).

Utzschneider KM, Prigeon RL, Faulenbach MV, et al. Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels. Diabetes Care. 2009;32(2):335-341. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.