Narcolepsy Criteria (Type 1 and Type 2)

Applies the third International Classification of Sleep Disorders criteria for narcolepsy.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Daily irrepressible sleep or lapses into sleep for at least three months
Yes
Mean sleep latency on the latency test
5 minutes
Sleep-onset REM periods on the latency test
1
A sleep-onset REM period on the overnight study
Yes
Other causes excluded
Yes

Result: type 2

The tool opens with these values already filled in. Replace them with your own.

What the result means

Type 1
Cataplexy with a mean latency of 8 minutes or less and two or more sleep-onset REM periods, or a spinal-fluid hypocretin-1 of 110 pg/mL or less on its own.
Type 2
The same latency findings with no cataplexy, the hypocretin unmeasured or above the line, and other causes excluded.
Both types
Daily irrepressible sleep or lapses into sleep for at least three months is required before either route is considered.
Cataplexy alone
Does not meet the criteria. It is half of one route and has to be paired with the latency findings, or replaced by the hypocretin result.
The overnight study
A sleep-onset REM period there may replace one of the two on the latency test, so a test showing one is not necessarily negative.
Low hypocretin
Type 1 whether or not there is cataplexy. The deficiency is the disease; cataplexy is a consequence not every patient has.
The exclusion
Too little sleep, untreated obstructive apnea, a delayed sleep phase and medication all produce a short latency with sleep-onset REM periods.

What you enter

  • Daily irrepressible sleep or lapses into sleep for at least three months
  • Cataplexy: brief loss of muscle tone triggered by emotion
  • Mean sleep latency on the latency test: the threshold is 8 or less
  • Sleep-onset REM periods on the latency test: the threshold is 2
  • A sleep-onset REM period on the overnight study, which may count as one of the two
  • Hypocretin-1 in the spinal fluid: 110 or less is type 1 on its own
  • Other causes excluded: too little sleep, obstructive apnea, a delayed sleep phase, medication
How this is calculated

American Academy of Sleep Medicine. International Classification of Sleep Disorders. 3rd ed. Darien, IL: AASM; 2014. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.