METAVIR Activity Grade (Liver Biopsy)

The METAVIR necroinflammatory activity grade on liver biopsy, the second axis of the METAVIR system, grades A0-A3, derived from the combination of piecemeal (interface) necrosis and lobular necrosis.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

METAVIR activity grade
A2 - moderate activity

Result: METAVIR A2: moderate necroinflammatory activity.

The tool opens with these values already filled in. Replace them with your own.

What the result means

A0
No necroinflammatory activity.
A1
Mild necroinflammatory activity.
A2
Moderate necroinflammatory activity.
A3
Severe necroinflammatory activity.

What you enter

  • METAVIR activity grade
How this is calculated

Bedossa P, Poynard T; The METAVIR Cooperative Study Group. An algorithm for the grading of activity in chronic hepatitis C. Hepatology. 1996;24(2):289-293. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.