Revised Mayo PSC Natural-History Model
Revised Mayo PSC natural-history model (Kim 2000): age, bilirubin, albumin, AST, and a history of variceal bleeding give a relative risk score banding survival in primary sclerosing cholangitis.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 55 years
- Bilirubin
- 5 mg/dL
- Albumin
- 3.0 g/dL
- AST
- 120 U/L
- History of variceal bleeding
- Yes
Result: Mayo PSC risk score 3.82 — high risk band.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Bands
- R < 0 low, 0–< 2 intermediate, ≥ 2 high. Higher = worse survival.
What you enter
- Age
- Bilirubin
- Albumin
- AST
- History of variceal bleeding
How this is calculated
- Formula
- R = 0.03 × age + 0.54 × ln(bilirubin) + 0.54 × ln(AST) + 1.24 × (variceal bleed) − 0.84 × albumin.
Kim WR, Therneau TM, Wiesner RH, et al. A revised natural history model for primary sclerosing cholangitis. Mayo Clin Proc. 2000;75(7):688-694. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.