Levodopa Equivalent Daily Dose (Jost 2023)
The levodopa equivalent daily dose of a Parkinson's disease regimen, by the 2023 factors.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Levodopa, immediate-release, total a day
- 600 mg
- Pramipexole, as salt, total a day
- 3 mg
- COMT inhibitor
- Opicapone
Result: Levodopa equivalent dose: 1,200 mg a day, from 3 items (Jost 2023 factors).
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Levodopa, immediate-release, total a day
- Levodopa, dual-release (Madopar DR), total a day
- Levodopa, controlled-release, total a day
- Levodopa, extended-release (Rytary), total a day
- Levodopa, inhaled (capsule dose), total a day
- Intrajejunal levodopa/carbidopa infusion (morning, maintenance and extra doses), total a day
- Intrajejunal levodopa/carbidopa/entacapone infusion: morning dose, total a day
- Intrajejunal levodopa/carbidopa/entacapone infusion: maintenance and extra doses, total a day
The other 25 fields
- Subcutaneous foslevodopa/foscarbidopa, total a day
- Selegiline, oral, total a day
- Selegiline, sublingual, total a day
- Rasagiline, total a day
- Pramipexole, as salt, total a day
- Pramipexole, as base, total a day
- Ropinirole, total a day
- Rotigotine, total a day
- Piribedil, total a day
- Apomorphine, subcutaneous, total a day
- Apomorphine, sublingual, total a day
- Lisuride, total a day
- Bromocriptine, total a day
- Pergolide, total a day
- Cabergoline, total a day
- Dihydroergocryptine, total a day
- Amantadine, immediate-release, total a day
- Amantadine, extended-release (Gocovri), total a day
- Amantadine, extended-release (Osmolex ER), total a day
- COMT inhibitor
- Levodopa equivalent covered by entacapone or tolcapone
- Istradefylline
- Safinamide 50 or 100 mg a day
- Zonisamide 25 or 50 mg a day
- Clinically effective anticholinergic single doses a day
How this is calculated
Citation
Jost ST, Kaldenbach MA, Antonini A, et al. Levodopa dose equivalency in Parkinson's disease: updated systematic review and proposals. Mov Disord 2023;38(7):1236-1252, Table 1. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.