Procedural sedation dosing (ketamine/propofol)

Procedural sedation dosing (ACEP): initial mg dose and syringe volume for ketamine (50 mg/mL), propofol (10 mg/mL), or 1:1 ketofol (5 mg/mL each) at the selected mg/kg, plus re-dose increment.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Agent
Ketamine (1-2 mg/kg, 50 mg/mL)
Weight
70 kg
Selected dose
1 mg/kg

Result: Ketamine 1 mg/kg x 70 kg = 70 mg = 1.4 mL at 50 mg/mL; re-dose ~35 mg.

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • Agent
  • Weight
  • Selected dose
How this is calculated

ACEP Clinical Policy on procedural sedation and analgesia (Ann Emerg Med. 2014;63(2):247-258); standard agent dosing: ketamine 1-2 mg/kg IV, propofol 0.5-1 mg/kg IV, ketofol per institutional 1:1 mix. No infusion automation. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.