ISARIC 4C Mortality Score (COVID-19)

ISARIC 4C Mortality Score (Knight 2020): a 0–21 in-hospital COVID-19 mortality score from age, sex, comorbidities, respiratory rate, SpO2, GCS, urea, and CRP.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Age
62
Sex
Male
Number of comorbidities
2
Respiratory rate
22
SpO2 on room air
95
Glasgow Coma Scale
15
Urea
5
Urea unit
Urea mmol/L
CRP
30

Result: ISARIC 4C 8 of 21 -- Intermediate risk group (in-hospital mortality ~9.9%). Contributions: age 62y +4, male +1, >=2 comorbidities +2, RR 22 +1.

The tool opens with these values already filled in. Replace them with your own.

What the result means

0-3
Low; in-hospital mortality ~1.2%.
4-8
Intermediate; ~9.9%.
9-14
High; ~31.4%.
>=15
Very high; ~61.5%.

What you enter

  • Age (years)
  • Sex
  • Number of comorbidities
  • Respiratory rate (/min)
  • SpO2 on room air (%)
  • Glasgow Coma Scale
  • Urea
  • Urea unit
  • CRP (mg/L)
How this is calculated

Knight SR, Ho A, Pius R, et al. Risk stratification of patients admitted to hospital with covid-19 using the ISARIC World Health Organization Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. BMJ. 2020;370:m3339. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.