Revised IPSET-thrombosis (essential thrombocythemia)
Revised IPSET-thrombosis (Barbui 2015): thrombotic-risk category in essential thrombocythemia from age > 60, prior thrombosis, and JAK2 V617F — very low / low / intermediate / high with the published annual rates.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age older than 60 years
- Yes
- History of thrombosis
- No
- JAK2 V617F mutation present
- Yes
Result: Revised IPSET-thrombosis: high risk (~2.36-4.17%/yr).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Very low
- No thrombosis history, no JAK2, age <= 60 (~0.44%/yr).
- Low
- JAK2 V617F only (~1.59%/yr).
- Intermediate
- Age > 60 without JAK2 or prior thrombosis (~1.44%/yr).
- High
- Prior thrombosis, or age > 60 with JAK2 (~2.36-4.17%/yr).
What you enter
- Age older than 60 years
- History of thrombosis
- JAK2 V617F mutation present
How this is calculated
Barbui T, Vannucchi AM, Buxhofer-Ausch V, et al. Practice-relevant revision of IPSET-thrombosis based on 1019 patients with essential thrombocythemia. Blood Cancer J. 2015;5(11):e369. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.