HFA-PEFF Diagnostic Score (ESC HFpEF algorithm)
HFA-PEFF diagnostic score (Pieske 2019): functional, morphological, and biomarker domains each scored none (0) / minor (1) / major (2); total 0-6 with >= 5 confirming and 2-4 an intermediate probability of HFpEF.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Functional domain
- major
- Morphological domain
- major
- Biomarker domain
- minor
Result: HFA-PEFF 5/6: HFpEF confirmed.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Domains
- functional, morphological, and biomarker domains; each scored on its highest criterion -- major 2, minor 1, capped at 2 per domain. Total 0-6.
- Verdict
- >= 5 HFpEF confirmed, 2-4 indeterminate (proceed to diastolic stress / invasive testing), <= 1 unlikely. Cross-links h2fpef.
What you enter
- Functional domain (echo E/e′, e′, TR velocity)
- Morphological domain (LAVI, LV mass, RWT)
- Biomarker domain (NT-proBNP / BNP)
How this is calculated
Pieske B, Tschope C, de Boer RA, et al. How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm (ESC Heart Failure Association). Eur Heart J. 2019;40(40):3297-3317. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.