InterTAK Diagnostic Score (takotsubo vs ACS)
InterTAK Diagnostic Score (Ghadri 2017): separates takotsubo syndrome from acute coronary syndrome.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Female sex
- Yes
- Emotional trigger
- Yes
- No ST depression, bar aVR
- Yes
Result: InterTAK 61 of 100 - low to intermediate probability of takotsubo syndrome.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 70 or less
- Low to intermediate probability. About 18% at 50 points. Consensus pathway: coronary angiography with left ventriculography.
- 70 or more
- High probability, about 90% above 70. Consensus pathway: consider transthoracic echocardiography.
- Disagreement
- Later validation cohorts report lower optimal cutoffs than 70. The consensus threshold is the one used here and the disagreement is stated, not settled.
- Caution
- A high score does not exclude a coronary occlusion, and this score decides nothing about angiography.
What you enter
- Female sex (25)
- Emotional trigger (24)
- Physical trigger (13)
- No ST depression, bar aVR (12)
- Psychiatric disorder (11)
- Neurologic disorder (9)
- QT prolongation (6)
How this is calculated
- Weights
- Female sex 25, emotional trigger 24, physical trigger 13, no ST depression except aVR 12, psychiatric disorder 11, neurologic disorder 9, QT prolongation 6. Maximum exactly 100.
Ghadri JR, Cammann VL, Jurisic S, et al. A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome. Eur J Heart Fail. 2017;19(8):1036-1042. Thresholds per the international expert consensus, Eur Heart J. 2018;39(22):2047-2062. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.