Leucovorin Rescue After High-Dose Methotrexate (Label Table)
Leucovorin rescue after high-dose methotrexate, matched to the leucovorin label's table.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Hours since the methotrexate infusion started
- 24 hours
- Serum methotrexate level
- 60
- Level unit
- µmol/L (micromolar)
- Baseline serum creatinine
- 0.7
- Current serum creatinine
- 0.9
Result: At 24 hours, 60 µmol/L is 50 µmol/L or more: the label's delayed early elimination or acute renal injury row.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Hours since the methotrexate infusion started
- Serum methotrexate level
- Level unit
- Baseline serum creatinine (optional; same unit as the current value)
- Current serum creatinine (optional)
- The 72-hour level, for a 96-hour level (optional)
How this is calculated
Citation
FDA labels on DailyMed: Leucovorin Calcium for Injection (Sagent), Leucovorin Rescue After High-Dose Methotrexate Therapy (the three-row table); Methotrexate Injection (Accord), sections 2.2 and 11 (molecular weight 454.44). Read the sources: Leucovorin Calcium for Injection label ↗, Methotrexate Injection label ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.