ADR Severity Level (Hartwig and Siegel)
Severity level 1 to 7 of an adverse drug reaction (Hartwig and Siegel), with its band.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Led directly or indirectly to death
- No
- Caused permanent harm
- No
- Needed intensive medical care
- No
- Added at least 1 day to the stay
- Yes
- Was the reason for admission
- No
- Suspected drug held, stopped or changed
- Yes
- Antidote or other treatment needed
- Yes
Result: Hartwig and Siegel level 4 (moderate): a level 3 reaction that added at least 1 day to the stay (level 4a).
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Led directly or indirectly to death
- Caused permanent harm
- Needed intensive medical care
- Added at least 1 day to the stay
- Was the reason for admission
- Suspected drug held, stopped or changed
- Antidote or other treatment needed
How this is calculated
Citation
Hartwig SC, Siegel J, Schneider PJ. Am J Hosp Pharm. 1992;49:2229-2232. Levels as reprinted by permission in Susilo R et al. J Multidiscip Healthc. 2022;15:1153 and in Manjhi PK et al. Cureus. 2024;16:e59975 (CC BY). Read the sources: Susilo 2022 (reprint) ↗, Manjhi 2024 (review) ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.