WHO-UMC Causality Category
WHO-UMC causality category for a suspected adverse drug reaction.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Time relationship to drug intake
- Reasonable
- Other causes
- Another cause is unlikely
- Response to withdrawal
- Response clinically reasonable
- Event definitive pharmacologically or phenomenologically
- No
- Rechallenge
- Not done
- More data needed or under examination
- No
- Information insufficient, cannot be supplemented
- No
Result: WHO-UMC category: Probable / Likely.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Time relationship to drug intake
- Other causes (disease or other drugs)
- Response to withdrawal
- Event definitive pharmacologically or phenomenologically
- Rechallenge
- More data needed or under examination
- Information insufficient, cannot be supplemented
How this is calculated
Citation
Uppsala Monitoring Centre. The use of the WHO-UMC system for standardised case causality assessment, Table 2 (categories and criteria restated in this tool's own words). Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.