Drug Level From an Actual Dose History (Superposition)
Drug level from the doses actually given, by one-compartment superposition, beside the level the same doses give on schedule.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Route
- IV bolus
- Doses, one per line
- 0, 1000 15, 1000
- Volume of distribution
- 50
- Half-life
- 12
- Scheduled interval
- 12
- Times to evaluate, semicolon-separated
- 24
Result: 16.89 mg/L at 24 h from the doses given, against 15 mg/L on schedule.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Route
- Doses, one per line: time, amount in mg
- Volume of distribution (L)
- Half-life (h)
- Clearance (L/h), in place of half-life
- Scheduled interval (h)
- Infusion duration (h)
- Oral absorption rate ka (per h)
The other 2 fields
- Oral bioavailability F (0 to 1)
- Times to evaluate, semicolon-separated
How this is calculated
Citation
Stated arithmetic: superposition of one-compartment curves for an IV bolus, a constant-rate infusion and first-order oral absorption (the Bateman function), one dose at a time. Linear kinetics only.
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.