Delta check (change from the last result)

Reports how far a result has moved from the last one on the same patient, three ways: the absolute difference, that difference as a percent of the previous result, and the rate per 24 hours of elapsed time.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Previous result
1.0
Current result, in the same units
2.4
Hours between the two results
12
Absolute delta threshold, if the laboratory has one
0.5

Result: flagged on the absolute delta, which is a reason to look and not a specimen problem

The tool opens with these values already filled in. Replace them with your own.

What the result means

Absolute delta
The current result minus the previous one.
Percent delta
That difference over the previous result. Undefined when the previous result was zero.
Rate
That difference per 24 hours. The same difference over six hours and over six days are not the same finding.
The thresholds
Local. There is no published universal set, and nothing here supplies one; with none entered, nothing is flagged.
A flag
A change, not an error. The check was invented to catch mislabeled specimens, and most of what it flags is real clinical change.
A better threshold
Where the biological variation of the analyte is known, the reference change value is the principled one.

What you enter

  • Previous result
  • Current result, in the same units
  • Hours between the two results
  • Absolute delta threshold, if the laboratory has one
  • Percent delta threshold, if the laboratory has one
  • Rate threshold per 24 hours, if the laboratory has one
How this is calculated

Ladenson JH. Patients as their own controls: use of the computer to identify "laboratory error". Clin Chem. 1975;21(11):1648-1653. Randell EW, Yenice S. Delta checks in the clinical laboratory. Crit Rev Clin Lab Sci. 2019;56(2):75-97. Read the sources: Ladenson 1975 ↗, Randell 2019 ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.