Inhibitor, Inducer or Substrate Strength From an Interaction Study (FDA)
FDA strength class of an observed exposure ratio from an interaction study: strong, moderate or weak inhibitor or inducer, or a sensitive substrate with a strong inhibitor.
Open the tool → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Which drug is classified
- The drug given with it (inhibitor or inducer)
- AUC ratio
- 6.2
Result: Strong inhibitor (AUC ratio 6.2).
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Which drug is classified
- AUC ratio (with / without)
- AUC with the other drug
- AUC without it
- Substrate study used a strong inhibitor
How this is calculated
Citation
FDA, Healthcare Professionals: FDA's Examples of Drugs that Interact with CYP Enzymes and Transporter Systems, Table 2 legend (inhibitor, inducer and substrate potency definitions), content current as of 05/29/2026. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.