CRRT effluent dose + citrate-Ca ratio
CRRT prescribed effluent dose from weight and prescribed effluent rate, against the 20-25 mL/kg/h KDIGO 2012 recommends delivering (which usually requires a higher prescription), with optional citrate-circuit calcium checks.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Patient weight
- 80 kg
- Prescribed effluent rate
- 1800 mL/h
- Modality
- CVVHDF
Result: Prescribed effluent dose 22.5 mL/kg/h (KDIGO 2012 target: 20-25 mL/kg/h delivered).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Prescribed <20 mL/kg/h
- Below the 20-25 mL/kg/h KDIGO 2012 recommends delivering.
- Prescribed 20-25 mL/kg/h
- The range KDIGO 2012 sets for the delivered dose, which usually requires a higher prescription.
- Prescribed >25 mL/kg/h
- Above the delivered-dose range, as KDIGO 2012 expects of a prescription; check the delivered dose.
- Total/ionized Ca >2.5
- Citrate toxicity likely per Davenport 2009 (both in mmol/L).
- Citrate circuit
- Davenport 2009: post-filter ionized Ca under 0.35 mmol/L; systemic ionized Ca 0.95-1.2 mmol/L.
What you enter
- Patient weight
- Prescribed effluent rate
- Modality
- Ultrafiltration
- Systemic ionized Ca
- Post-filter ionized Ca
- Total Ca
How this is calculated
Citation
KDIGO AKI Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl. 2012;2(1):1-138 (rec. 5.8.4: deliver 20-25 mL/kg/h). Davenport A, Tolwani A. Citrate anticoagulation for CRRT in AKI. NDT Plus. 2009;2(6):439-447 (citrate-Ca targets). Read the sources: KDIGO 2012 ↗, Davenport 2009 ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.