CARG Chemotherapy Toxicity Tool
CARG chemotherapy-toxicity score (Hurria 2011): a weighted geriatric-assessment sum stratifying the risk of grade 3–5 chemotherapy toxicity in older adults.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age ≥ 72 years
- Yes
- GI or GU cancer
- Yes
- Standard-dose chemotherapy
- Yes
Result: CARG score 6: intermediate risk — about 52% grade 3–5 toxicity.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Predictors
- age ≥ 72 (2), GI/GU cancer (2), standard-dose chemo (2), polychemo (2), low Hgb (3), CrCl < 34 (3), hearing (2), ≥ 1 fall (3), med help (1), walking limit (2), low social activity (1).
- Bands
- low 0–5 (~30% grade 3–5 toxicity), intermediate 6–9 (~52%), high ≥ 10 (~83%). Compute CrCl on the Cockcroft–Gault tool.
What you enter
- Age ≥ 72 years
- GI or GU cancer
- Standard-dose chemotherapy
- Polychemotherapy (> 1 agent)
- Hemoglobin < 11 (M) / < 10 (F) g/dL
- Creatinine clearance < 34 mL/min
- Hearing fair or worse
- ≥ 1 fall in the last 6 months
The other 3 fields
- Needs help taking medications
- Limited in walking one block
- Decreased social activity
How this is calculated
Hurria A, Togawa K, Mohile SG, et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol. 2011;29(25):3457-3465. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.