AST/ALT (De Ritis) Ratio
AST/ALT (De Ritis) ratio: AST / ALT; < 1 suggests NAFLD/viral/acute injury, 1–2 advanced fibrosis, and > 2 classic alcoholic liver disease.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- AST
- 60 IU/L
- ALT
- 30 IU/L
Result: AST/ALT ratio 2 — 1-2: suggests advanced fibrosis/cirrhosis.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- < 1
- Typical of NAFLD, viral, or acute injury.
- 1-2
- Suggests advanced fibrosis/cirrhosis.
- > 2
- Classic for alcoholic liver disease. A ratio, not a diagnosis.
What you enter
- AST
- ALT
How this is calculated
De Ritis F, Coltorti M, Giusti G. An enzymic test for the diagnosis of viral hepatitis: the transaminase serum activities. Clin Chim Acta. 1957;2(1):70-74. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.