ARC-HBR Criteria (High Bleeding Risk after PCI)
The ARC-HBR criteria (Academic Research Consortium for High Bleeding Risk, Urban and colleagues 2019) define high bleeding risk in patients undergoing percutaneous coronary intervention.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Sex
- male
- Age
- 80 years
- Hemoglobin
- 14 g/dL
- eGFR
- 45 mL/min
- Platelet count
- 250 x10^9/L
- Prior spontaneous bleeding
- No prior spontaneous bleeding requiring hospitalization or transfusion
- Prior ischemic stroke
- No previous ischemic stroke
- Anticipated long-term oral anticoagulation
- No
- Chronic bleeding diathesis
- No
- Liver cirrhosis with portal hypertension
- No
The other 7 values
- Active malignancy within 12 months, excluding non-melanoma skin cancer
- No
- Previous SPONTANEOUS intracranial hemorrhage, AT ANY TIME
- No
- Previous TRAUMATIC intracranial hemorrhage within 12 months
- No
- Brain arteriovenous malformation
- No
- Non-deferrable major surgery expected while on dual antiplatelet therapy
- No
- Major surgery or major trauma within 30 days before PCI
- No
- Long-term oral NSAIDs or corticosteroids
- No
Result: High bleeding risk
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Common error
- A widely used calculator states the rule as "at least 1 major", which misses every patient qualifying on minors alone.
- Banding
- Anemia, eGFR, prior bleeding and prior stroke are BANDED across major and minor - NOT separate criteria. The same patient cannot be both.
- Anemia
- Under 11 g/dL MAJOR (both sexes). Minor band 11-12.9 men, 11-11.9 women. SEX MATTERS ONLY IN THE MINOR BAND.
- eGFR
- Under 30 MAJOR; 30-59 MINOR.
- Platelets
- Under 100 x10^9/L MAJOR.
- Age
- 75 or over MINOR.
- Timing
- SIX different windows: 6 months, 6-12 months, 12 months, any time, 30 days. Do not carry one across the set.
- Target
- A DEFINITION, not a score: BARC 3-5 bleeding at or above 4% or ICH at or above 1% at 1 year. Counts are provenance, not severity.
- Scope
- Bleeding risk only. Does NOT weigh against ischemic risk. Not an instruction to shorten DAPT or drop an agent.
What you enter
- Sex.
- Hemoglobin.
- eGFR.
- Platelet count.
- Age.
- Prior spontaneous bleeding.
- Prior ischemic stroke.
- Anticipated long-term oral anticoagulation.
- Chronic bleeding diathesis.
- Liver cirrhosis with portal hypertension.
The other 7 fields
- Sex. Used ONLY for the anemia MINOR band (11 to 12.9 for men, 11 to 11.9 for women). The major anemia threshold is the same for both.
- Hemoglobin. BANDED: under 11 is MAJOR, the sex-specific band above it is MINOR, and the same patient cannot be both.
- eGFR. BANDED: under 30 is MAJOR, 30 to 59 is MINOR.
- Platelet count. Under 100 is a MAJOR criterion.
- Age. 75 or over is a MINOR criterion.
- Prior spontaneous bleeding. BANDED across major and minor by TIMING [none = no criterion; within-6-months-or-recurrent = major; six-to-twelve-months = minor]
- Prior ischemic stroke. BANDED across major and minor [none = no criterion; moderate-severe-within-6-months = major; other-ischemic-any-time = minor]
- Anticipated long-term oral anticoagulation. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Chronic bleeding diathesis. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Liver cirrhosis with portal hypertension. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Active malignancy within 12 months, excluding non-melanoma skin cancer. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Previous SPONTANEOUS intracranial hemorrhage, AT ANY TIME. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Previous TRAUMATIC intracranial hemorrhage within 12 months. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Brain arteriovenous malformation. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Non-deferrable major surgery expected while on dual antiplatelet therapy. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Major surgery or major trauma within 30 days before PCI. A MAJOR criterion: one alone makes the patient high bleeding risk.
- Long-term oral NSAIDs or corticosteroids. A MINOR criterion: two minor criteria together make the patient high bleeding risk.
How this is calculated
- Rule
- 1 MAJOR criterion OR 2 MINOR criteria. Two minor are worth one major, so minor criteria ALONE can qualify a patient.
Urban P, Mehran R, Colleran R, et al. Defining high bleeding risk in patients undergoing percutaneous coronary intervention: a consensus document from the Academic Research Consortium for High Bleeding Risk. Circulation. 2019;140(3):240-261. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.