UGT1A1 Genotype and the Irinotecan Label

What the irinotecan label says for a UGT1A1 genotype.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

UGT1A1 genotype on the report
*28/*28

Result: UGT1A1 *28/*28: the label says to consider reducing the starting dose by at least one level.

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • UGT1A1 genotype on the report
How this is calculated

Citation

Irinotecan Hydrochloride Injection label (Bluepoint Laboratories), section 2.3, Dosage in Patients with Reduced UGT1A1 Activity. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.