Stool Osmotic Gap

Stool osmotic gap (Eherer & Fordtran 1992): 290 − 2·(stool Na + stool K); > 100 osmotic, < 50 secretory diarrhea.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Stool sodium
30 mEq/L
Stool potassium
15 mEq/L

Result: Stool osmotic gap 200 mOsm/kg — osmotic diarrhea (gap > 100).

The tool opens with these values already filled in. Replace them with your own.

What the result means

Interpretation
> 100 osmotic diarrhea, < 50 secretory, 50–100 indeterminate.

What you enter

  • Stool sodium
  • Stool potassium
How this is calculated
Formula
Gap = 290 − 2·(stool Na + stool K), fixed 290 mOsm/kg.

Eherer AJ, Fordtran JS. Fecal osmotic gap and pH in experimental diarrhea of various causes. Gastroenterology. 1992;103(2):545-551. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

Browse all tools

Built by Clay Good. Source on GitHub.