SIRS Criteria (with Sepsis-3 context)
SIRS criteria (Bone 1992): temperature > 38 or < 36 C, HR > 90, RR > 20 or PaCO2 < 32, WBC > 12 or < 4 or > 10% bands; >= 2 of 4 is SIRS-positive.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Temperature > 38 C or < 36 C
- Yes
- Heart rate > 90 bpm
- Yes
- RR > 20/min or PaCO2 < 32 mmHg
- Yes
- WBC > 12 or < 4 (x10^9/L) or > 10% bands
- No
Result: SIRS-positive (3 of 4 criteria) per Bone 1992. Sepsis-3 (Singer 2016) deprecated SIRS for sepsis screening in favor of qSOFA / SOFA.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0-1 of 4
- SIRS-negative per Bone 1992.
- >=2 of 4
- SIRS-positive per Bone 1992. Sepsis-3 (Singer 2016) replaced SIRS with qSOFA / SOFA for sepsis screening.
What you enter
- Temperature > 38 C or < 36 C
- Heart rate > 90 bpm
- RR > 20/min or PaCO2 < 32 mmHg
- WBC > 12 or < 4 (x10^9/L) or > 10% bands
How this is calculated
Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. Chest. 1992;101(6):1644-1655. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.