Systemic Immune-Inflammation Index (SII)
Systemic immune-inflammation index: platelets × neutrophils / lymphocytes; a composite inflammatory marker whose interpretation is context-dependent.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Platelet count
- 300 ×10⁹/L
- Absolute neutrophil count
- 6 ×10⁹/L
- Absolute lymphocyte count
- 1.5 ×10⁹/L
Result: Systemic immune-inflammation index 1200 — interpretation is context-dependent.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- value
- SII = platelets x ANC / ALC. Higher values reflect a more pro-inflammatory state and track with a worse prognosis across many conditions. No universal cutoff.
What you enter
- Platelet count
- Absolute neutrophil count
- Absolute lymphocyte count
How this is calculated
Hu B, Yang XR, Xu Y, et al. Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin Cancer Res. 2014;20(23):6212-6222. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.