RoPE Score (Risk of Paradoxical Embolism)

Applies the RoPE index (Risk of Paradoxical Embolism) after a cryptogenic stroke in which a patent foramen ovale was found.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Age
32 years
No history of high blood pressure
Yes
No history of diabetes
Yes
No previous stroke or transient ischemic attack
Yes
Nonsmoker
Yes
Cortical infarct on imaging
Yes

Result: 9 of 10

The tool opens with these values already filled in. Replace them with your own.

What the result means

0 to 3
About 0 percent of strokes at this score are caused by the hole. Two-year recurrence of stroke or transient ischemic attack about 20 percent.
4
Attributable fraction about 38 percent. Two-year recurrence about 12 percent.
5
Attributable fraction about 34 percent, below the figure at 4 in the published table. Two-year recurrence about 7 percent.
6
Attributable fraction about 62 percent. Two-year recurrence about 8 percent.
7
Attributable fraction about 72 percent. Two-year recurrence about 6 percent.
8
Attributable fraction about 84 percent. Two-year recurrence about 6 percent.
9 to 10
About 88 percent of strokes at this score are caused by the hole. Two-year recurrence about 2 percent.
Not a risk score
The attributable fraction rises with the score while recurrence falls. A high number means the hole is more likely the cause AND another stroke is less likely.
Age is most of it
Age supplies up to 5 of the 10 points and the history items are all the absence of vascular disease, which is itself age-correlated.

What you enter

  • Age
  • No history of high blood pressure
  • No history of diabetes
  • No previous stroke or transient ischemic attack
  • Nonsmoker
  • Cortical infarct on imaging
How this is calculated

Kent DM, Ruthazer R, Weimar C, et al. An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke. Neurology. 2013;81(7):619-625. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.