Rh immune globulin dose (fetomaternal hemorrhage)
RhIG (anti-D) dosing after fetomaternal hemorrhage: FMH mL = maternal blood volume x Kleihauer-Betke fetal-cell fraction, then number of standard 300 ug RhoGAM vials per the AABB rounding rule.
Open the tool → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Maternal blood volume
- 5000 mL
- Fetal cells on Kleihauer-Betke
- 1.5 %
Result: Fetomaternal hemorrhage 75 mL; 4 standard 300 ug vials of RhIG.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Maternal blood volume (mL)
- Fetal cells on Kleihauer-Betke (%)
How this is calculated
Sandler SG, Gottschall JL. Postpartum Rh immunoprophylaxis. Obstet Gynecol. 2012;120(6):1428-1438; AABB Technical Manual. One 300 ug vial per 30 mL fetal whole blood; round, then add one vial. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.