Reynolds Risk Score (hsCRP + family history)
Reynolds Risk Score (Ridker 2007/2008): 10-year cardiovascular risk adding high-sensitivity CRP and family history of premature MI to age, sex, BP, lipids, and smoking (with HbA1c for diabetic women).
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 60 years
- Male sex
- No
- Systolic BP
- 140 mmHg
- Total cholesterol
- 260 mg/dL
- HDL cholesterol
- 45 mg/dL
- High-sensitivity CRP
- 4.5 mg/L
- Current smoker
- Yes
- Family history of premature MI
- Yes
Result: Reynolds 10-year cardiovascular risk 18.9%.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Output
- 10-year risk of MI, stroke, revascularization, or cardiovascular death. Cross-links ascvd / prevent.
What you enter
- Age
- Male sex
- Systolic BP
- Total cholesterol
- HDL cholesterol
- High-sensitivity CRP
- Current smoker
- Family history of premature MI
The other 2 fields
- Diabetes mellitus
- HbA1c (optional, diabetic women)
How this is calculated
- Model
- adds high-sensitivity CRP (mg/L) and parental history of premature MI to the traditional factors. Women use linear age plus an HbA1c term for diabetics; the men's model is for non-diabetics.
Ridker PM, Buring JE, Rifai N, Cook NR. Development and validation of improved algorithms for global cardiovascular risk assessment in women: the Reynolds Risk Score. JAMA. 2007;297(6):611-619; Ridker PM, et al. Circulation. 2008;118(22):2243-2251 (men). Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.