Expected HCO3 (respiratory acidosis)

Expected HCO3 in respiratory acidosis (Brackett 1965 acute; Schwartz 1965 chronic): the appropriate-compensation band vs the measured HCO3.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Measured PaCO2
60 mmHg
Measured HCO3
26 mEq/L
Acute or chronic
Acute

Result: Expected HCO3 26 mEq/L (acute, +1 per 10 mmHg): the measured 26 mEq/L matches the expected 26 mEq/L (+/-2), consistent with appropriate compensation.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Reading
a measured HCO3 below the expected band suggests an added metabolic acidosis; above it, an added metabolic alkalosis.

What you enter

  • Measured PaCO2
  • Measured HCO3
  • Acute or chronic
How this is calculated
Formula
expected HCO3 = 24 + k x (PaCO2 - 40)/10; k = 1 acute, 4 chronic (3.5-4 range).

Brackett NC Jr, Cohen JJ, Schwartz WB. Carbon dioxide titration curve of normal man. N Engl J Med. 1965;272:6-12; chronic adaptation per Schwartz WB, et al. 1965. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.