nPCR / nPNA (dialysis protein catabolic rate)
Normalized protein catabolic rate (nPCR / nPNA) from the interdialytic BUN rise: a surrogate of dietary protein intake in g/kg/day against the ~1.0-1.2 g/kg/day nutrition target.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Post-dialysis BUN
- 24 mg/dL
- Pre-dialysis BUN
- 70 mg/dL
- Interdialytic interval
- 44 hours
Result: nPCR 1.12 g/kg/day: within the ~1.0-1.2 g/kg/day nutrition target.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Target
- nutrition target roughly 1.0-1.2 g/kg/day; below about 0.8 suggests inadequate protein intake.
What you enter
- Post-dialysis BUN
- Pre-dialysis BUN (next session)
- Interdialytic interval
How this is calculated
- Formula
- nPCR (g/kg/day) = 0.22 + 0.864 x (pre-dialysis BUN - post-dialysis BUN) / interdialytic hours; the two-point anuric urea-kinetic form.
Depner TA, Daugirdas JT. Equations for normalized protein catabolic rate based on two-point modeling of hemodialysis urea kinetics. J Am Soc Nephrol. 1996;7(5):780-785. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.