Bacterial Meningitis Score (Nigrovic)
Bacterial Meningitis Score (Nigrovic 2007): positive CSF Gram stain (2), then CSF ANC >= 1000, CSF protein >= 80, peripheral ANC >= 10,000, and seizure at/before presentation (1 each).
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Positive CSF Gram stain
- No
- CSF ANC >= 1000 cells/mm^3
- Yes
- CSF protein >= 80 mg/dL
- Yes
- Peripheral ANC >= 10,000 cells/mm^3
- No
- Seizure at or before presentation
- No
Result: Nigrovic 2: NOT low risk for bacterial meningitis per Nigrovic 2007 (>=1); do not discharge.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0
- Very low risk for bacterial meningitis per Nigrovic 2007 (NPV ~99.9%).
- >=1
- Not low risk per Nigrovic 2007; do not discharge.
What you enter
- Positive CSF Gram stain (2)
- CSF ANC >= 1000 cells/mm^3 (1)
- CSF protein >= 80 mg/dL (1)
- Peripheral ANC >= 10,000 cells/mm^3 (1)
- Seizure at or before presentation (1)
How this is calculated
Nigrovic LE, Kuppermann N, Macias CG, et al. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA. 2007;297(1):52-60. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.