Magnesium sulfate (preeclampsia / eclampsia)

Magnesium sulfate for preeclampsia/eclampsia (ACOG PB 222, Magpie): loading volume for the 4 or 6 g load and maintenance mL/h at the bag concentration, halved in renal impairment.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Loading dose
4 g
Maintenance rate
2 g/h
Bag concentration
0.04 g/mL

Result: Loading 4 g = 100 mL over 20-30 min; maintenance 2 g/h = 50 mL/h.

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • Loading dose
  • Maintenance rate
  • Bag concentration
  • Renal impairment
How this is calculated

ACOG Practice Bulletin 222, Gestational Hypertension and Preeclampsia (2020); Magpie Trial (Lancet. 2002;359(9321):1877-1890). 4-6 g load over 20-30 min, 1-2 g/h maintenance; renal impairment halves the maintenance default. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.