Lactate Clearance
Lactate clearance: (initial - repeat) / initial x 100; a clearance >= 10% is the cited favorable early-resuscitation range.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Initial lactate
- 4.0 mmol/L
- Repeat lactate
- 2.0 mmol/L
Result: Lactate clearance 50% (4 -> 2 mmol/L): >= 10%, the cited favorable early-clearance range.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Interpretation
- a clearance of >= 10% over the early hours is the cited favorable range; a negative value means the lactate rose.
What you enter
- Initial lactate
- Repeat lactate
How this is calculated
- Formula
- clearance = (initial - repeat) / initial x 100; the initial lactate must be > 0.
Nguyen HB, Rivers EP, Knoblich BP, Jacobsen G, Muzzin A, Ressler JA, Tomlanovich MC. Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med. 2004;32(8):1637-1642. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.