ICHD-3 Criteria (Indomethacin-Responsive Headaches)

Applies the ICHD-3 criteria for the two indomethacin-responsive headaches.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Number of attacks
30
Attack duration, minutes
15
Attacks per day
8
Miosis or ptosis
Yes
Absolute response to indomethacin
Yes
No better ICHD-3 explanation
Yes

Result: 3.2 Paroxysmal hemicrania

The tool opens with these values already filled in. Replace them with your own.

What the result means

3.2
At least 20 attacks of severe one-sided orbital, supraorbital or temporal pain lasting 2 to 30 minutes, MORE than 5 a day.
3.4
One-sided headache present for more than 3 months, with exacerbations of moderate or greater intensity.
Shared C
Either or both: at least one ipsilateral cranial autonomic sign, or restlessness or agitation.
The criterion that is a drug
BOTH require an ABSOLUTE response to therapeutic indomethacin. It is a diagnostic criterion, not a consequence, so neither can be diagnosed before an adequate trial has been done and worked.
Dose
ICHD-3 notes that in an adult, oral indomethacin should start at at least 150 mg daily and rise if needed to 225 mg daily.
Versus cluster
Paroxysmal hemicrania is the diagnosis most often mistaken for cluster headache. Shorter and more frequent: 2 to 30 minutes more than 5 a day, against 15 to 180 minutes up to 8 a day.
One asymmetry
Hemicrania continua accepts aggravation of the pain by movement as an alternative in criterion C. Paroxysmal hemicrania does not.

What you enter

  • Absolute response to indomethacin
  • Number of attacks
  • Attack duration, minutes
  • Attacks per day
  • Continuous one-sided headache
  • Months present
  • Exacerbations of moderate or greater intensity
  • Conjunctival injection or tearing
The other 7 fields
  • Nasal congestion or rhinorrhea
  • Eyelid edema
  • Forehead and facial sweating
  • Miosis or ptosis
  • Restlessness or agitation
  • Pain worse with movement (3.4 only)
  • No better ICHD-3 explanation
How this is calculated

Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211, sections 3.2 and 3.4. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.