Hepatic Steatosis Index (NAFLD screen)
Hepatic Steatosis Index (Lee 2010): 8 × (ALT/AST) + BMI + 2 (female) + 2 (diabetes); above 36 makes NAFLD likely.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- ALT
- 60
- AST
- 30
- BMI
- 30
- Female sex
- Yes
- Diabetes mellitus
- Yes
Result: Hepatic Steatosis Index 50: above 36 -- NAFLD is likely (consider further workup).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Thresholds
- below 30 rules NAFLD out (sensitivity ~93%); above 36 rules it in (specificity ~92%); 30-36 indeterminate.
What you enter
- ALT (U/L)
- AST (U/L)
- BMI (kg/m²)
- Female sex
- Diabetes mellitus
How this is calculated
- Formula
- HSI = 8 x (ALT/AST) + BMI + 2 if female + 2 if diabetes.
Lee JH, Kim D, Kim HJ, et al. Hepatic steatosis index: a simple screening tool reflecting nonalcoholic fatty liver disease. Dig Liver Dis. 2010;42(7):503-508. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.