HELLP Syndrome Criteria
HELLP syndrome criteria (Sibai 1990): hemolysis, elevated liver enzymes (AST >= 70), and low platelets (< 100) - all three is complete, one or two is partial.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Hemolysis
- No
- Elevated liver enzymes
- No
- Low platelets
- No
Result: HELLP: no HELLP criteria met per Sibai 1990.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0 criteria
- No HELLP criteria met per Sibai 1990.
- 1-2 criteria
- Partial HELLP per Sibai 1990.
- 3 criteria
- Complete HELLP per Sibai 1990.
- Mississippi class 1
- Platelet nadir <=50 x10^9/L per Martin 1999.
- Mississippi class 2
- Platelet nadir 50-100 x10^9/L per Martin 1999.
- Mississippi class 3
- Platelet nadir 100-150 x10^9/L per Martin 1999.
What you enter
- Hemolysis (abnormal smear / bilirubin >= 1.2 / LDH >= 600)
- Elevated liver enzymes (AST >= 70 U/L)
- Low platelets (< 100 x10^9/L)
- Platelet nadir for Mississippi class (x10^9/L, optional)
How this is calculated
Sibai BM. The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much ado about nothing? Am J Obstet Gynecol. 1990;162(2):311-316. (Mississippi classification: Martin JN Jr, et al. Am J Obstet Gynecol. 1999;180(6):1373-1384.) Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.