Carrier Frequency From Disease Incidence (Hardy-Weinberg)
Carrier frequency 2pq from the incidence of an autosomal recessive condition, or from the allele frequency.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Enter
- Incidence of the condition (affected)
- Incidence, as 1 in N, a fraction, a percent or a decimal
- 1 in 2500
Result: Carrier frequency 2pq = 0.0392 (1 in 26), from q = 0.02 and p = 0.98.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Enter
- Incidence, as 1 in N, a fraction, a percent or a decimal
- Allele frequency q
How this is calculated
Citation
Hardy GH. Mendelian proportions in a mixed population. Science 1908;28(706):49-50 (read in the copy at esp.org): the stable distribution p : 2q : r with q squared = pr under random mating. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.