EUTOS Score (CML Prognosis on Imatinib)

EUTOS score (Hasford 2011): peripheral-blood basophils and spleen size predict 18-month complete cytogenetic response in chronic-phase CML on imatinib; > 87 marks high risk.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Basophils
8
Spleen size
12

Result: EUTOS 104 — high risk (> 87): lower 18-month complete-cytogenetic-response and progression-free-survival rates.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Bands
> 87 high risk, ≤ 87 low risk, for the 18-month complete cytogenetic response and progression-free survival on front-line imatinib. A risk stratifier, not a treatment order.

What you enter

  • Basophils (% of peripheral blood)
  • Spleen size (cm below costal margin; 0 if not palpable)
How this is calculated
Formula
EUTOS = 7 × basophils (% of peripheral blood at baseline) + 4 × spleen size (cm below the costal margin, 0 if not palpable).

Hasford J, Baccarani M, Hoffmann V, et al. Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score. Blood. 2011;118(3):686-692. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.