DENOVA Score (Echo Need in E. faecalis Bacteremia)

DENOVA score (Berge 2019): in Enterococcus faecalis bacteremia — symptom duration ≥ 7 days, embolization, ≥ 2 positive cultures, unknown origin, valve disease, and murmur (0–6); ≥ 3 warrants echocardiography.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Duration of symptoms ≥ 7 days
Yes
Embolization
No
≥ 2 positive cultures
Yes
Origin of infection unknown
No
Valve disease
No
Auscultated murmur
Yes

Result: DENOVA score 3 — echocardiography recommended (>= 3).

The tool opens with these values already filled in. Replace them with your own.

What the result means

<= 2
Echocardiography can be omitted.
>= 3
Echocardiography recommended. Duration, embolization, >= 2 cultures, origin unknown, valve disease, murmur. A decision rule, not an imaging order.

What you enter

  • Duration of symptoms ≥ 7 days (+1)
  • Embolization (+1)
  • ≥ 2 positive cultures (+1)
  • Origin of infection unknown (+1)
  • Valve disease (+1)
  • Auscultated murmur (+1)
How this is calculated

Berge A, Krantz A, Ostlund H, Naucler P, Rasmussen M. The DENOVA score efficiently identifies patients with monomicrobial Enterococcus faecalis bacteremia where echocardiography is not necessary. Infection. 2019;47(1):45-50. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.