DAS28 (rheumatoid arthritis disease activity, ESR/CRP)

DAS28 rheumatoid-arthritis disease-activity score from the 28-joint tender and swollen counts, the ESR or CRP marker (form-specific), and the patient global VAS; banded by EULAR cutoffs.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

28-joint tender count
8
28-joint swollen count
4
Inflammatory-marker form
ESR (DAS28-ESR)
ESR
30 mm/hr
Patient global health VAS
50

Result: DAS28-ESR 5.22 — high disease activity (EULAR).

The tool opens with these values already filled in. Replace them with your own.

What the result means

EULAR bands
Remission < 2.6; low activity 2.6–3.2; moderate activity 3.2–5.1; high activity > 5.1.

What you enter

  • 28-joint tender count
  • 28-joint swollen count
  • Inflammatory-marker form
  • ESR (if form = esr)
  • CRP (if form = crp)
  • Patient global health VAS (0–100)
How this is calculated
Formula
DAS28-ESR = 0.56·√TJC28 + 0.28·√SJC28 + 0.70·ln(ESR) + 0.014·GH. DAS28-CRP = 0.56·√TJC28 + 0.28·√SJC28 + 0.36·ln(CRP+1) + 0.014·GH + 0.96. The two forms are not interchangeable.

Prevoo MLL, van 't Hof MA, Kuper HH, et al. Modified disease activity scores that include twenty-eight-joint counts. Arthritis Rheum. 1995;38(1):44-48. CRP form: Wells G, et al. Ann Rheum Dis. 2009;68(6):954-960. EULAR cutoffs. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.