Acute Cholangitis Diagnosis (Tokyo Guidelines TG18)

Acute cholangitis diagnosis (Tokyo Guidelines TG18/TG13, Kiriyama 2018): classifies a presentation as definite, suspected, or not-met from three categories.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

A-1 fever and/or shaking chills
Yes
B-1 jaundice
Yes

Result: Suspected acute cholangitis (TG18): one item in category A (fever) plus one in B (jaundice); a definite diagnosis needs one item in each of A, B, and C.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Suspected
One item in A (systemic inflammation) plus one item in either B (cholestasis) or C (imaging).
Definite
One item in each of A, B, and C.
Not met
Fewer items than the suspected threshold; the presentation does not meet TG18 criteria.

What you enter

  • A-1 fever and/or shaking chills (BT > 38 C)
  • A-2 lab evidence of inflammatory response (WBC < 4 or > 10 x1000/uL, or CRP >= 1 mg/dL)
  • B-1 jaundice (total bilirubin >= 2 mg/dL)
  • B-2 abnormal liver function tests (ALP, GGT, AST, or ALT > 1.5x upper limit of normal)
  • C-1 biliary dilatation on imaging
  • C-2 evidence of the etiology on imaging (stricture, stone, stent, etc.)
How this is calculated

Miura F, Okamoto K, Takada T, et al. Tokyo Guidelines 2018: initial management of acute biliary infection and flowchart for acute cholangitis. J Hepatobiliary Pancreat Sci. 2018;25(1):31-40 (Table 1, cited from Kiriyama et al.). Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

Browse all tools

Built by Clay Good. Source on GitHub.