Bloodborne Pathogen Exposure Decision Tree
Bloodborne Pathogen Exposure Decision Tree - a deterministic tool in Sophie Well's Immunization & Infectious Disease group.
Open the Bloodborne Pathogen Exposure Decision Tree → Runs in your browser. No signup, no tracking.
What this is
Walk the CDC bloodborne-pathogen exposure decision tree for occupational and non-occupational exposures to HIV, hepatitis B, and hepatitis C. Sophie Well asks about the exposure type (percutaneous, mucous-membrane, non-intact-skin, or sexual), the source patient's known status and viral load if available, the exposed person's hepatitis B vaccination and antibody status, and the time elapsed since the exposure, and returns the recommended testing schedule and prophylaxis: HIV PEP regimen and 28-day duration, HBV immune globulin and vaccine series considerations, and HCV surveillance. Source: CDC USPHS occupational and non-occupational HIV PEP guidance; CDC HBV/HCV exposure management.
When to use it
Use this in employee health, the ED, or a sexual-assault evaluation when a needlestick, splash, or non-occupational exposure happens and the right next steps depend on a fast risk assessment. The 72-hour window for HIV PEP is the hard constraint - sooner is better, and the regimen drops in effectiveness rapidly after that point. HBV PEP timing is generous (within 7 days for HBIG, within 24 hours for vaccine if unvaccinated); HCV has no PEP and the play is baseline-and-follow-up testing with early treatment if seroconversion occurs. State and local public-health guidance and the source patient's actual labs override the algorithm when they are available.
References
CDC USPHS guidance for occupational and non-occupational HIV PEP; HBV/HCV exposure management.
Source: CDC HIV/HBV/HCV bloodborne pathogen exposure recommendations
Sophie Well is a reference and educational tool. Not medical, legal, or financial advice. Does not replace clinician judgment, professional billing review, or legal counsel.