Aldosterone-Renin Ratio (ARR, primary-aldosteronism screen)
Aldosterone-renin ratio for primary-aldosteronism screening: plasma aldosterone (ng/dL) ÷ renin, with the positive-screen cutoff read against the renin assay unit (PRA vs DRC) and aldosterone ≥ 15 ng/dL.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Plasma aldosterone
- 22 ng/dL
- Renin value
- 0.5
- Renin assay unit
- Plasma renin activity — PRA (ng/mL/h)
Result: ARR 44 — positive screen.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Cutoffs
- PRA (ng/mL/h): ARR ~20–40 with aldosterone ≥ 15 ng/dL; DRC (mIU/L): ARR ~3.7. A positive screen warrants confirmatory testing.
What you enter
- Plasma aldosterone
- Renin value (> 0)
- Renin assay unit (PRA ng/mL/h or DRC mIU/L)
How this is calculated
- Formula
- ARR = plasma aldosterone (ng/dL) ÷ renin. The cutoff differs by renin unit and is never compared across unit systems.
Funder JW, Carey RM, Mantero F, et al. The management of primary aldosteronism: case detection, diagnosis, and treatment — an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2016;101(5):1889-1916. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.